Download International Review of Cytology, Vol. 87 by G.H. Bourne (ed.), J.F. Danielli (ed.) PDF

By G.H. Bourne (ed.), J.F. Danielli (ed.)

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Lipid-mediated protein-protein interactions, although potentially selective in nature, are really one manifestation of the overall problem of protein solubility within the bilayer. Two widely known structures to which protein insolubility may contribute are gap junctions and the purple membrane of Halobacterium. In both cases there is long-range membrane order due to laterally separated arrays to densely packed integral proteins, and in neither case are cytoskeletal components implicated as a stabilizing factor.

B. Biological Scope of Measurements........................ C. Temperature Dependency . . . . . . . . . . . . . . . . D. Short- versus Long-Range Diffusion E. Diffusional Constraints . . . . . . . . . . . . . . . . . 111. Implications in Membrane Biology. A. Pattern Creation and Maintenance ........................ B. Reactions in Two Dimensions.. C. Biological Signaling at the Membrane D. Self-Assembly and Sorting ..............................

Saffman-Delbruck theory is a hydrodynamic model which treats the membrane as a featureless continuum characterized by a bulk viscosity. , 1977, for evidence on photoreceptor disk membrane). , 1983) can apparently undergo independent phase changes. Diffusion in isotropic fluids may depend upon density fluctuations which open up local voids of free volume (Cohen and Turnbull, 1959). , 1981); the coat protein of M-13 phage (Smith ef 01.. 1979~);cytochrorne P-450 (Wu and Yang, 1980); and lipophilin (Derzko and Jacobson, 1978).

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