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By J. Dodgson, R. I. Mccallum and M. R. Bailey (Eds.)

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Extra resources for Inhaled Particles VI. Proceedings of an International Symposium and Workshop on Lung Dosimetry Organised by the British Occupational Hygiene Society in Co-Operation with the Commission of the European Communities, Cambridge, 2–6 September 1985

Sample text

A. < 05-Γ δ 0*4- T04! * t -8s T0·3! 3Î T0,2! 1 1—M-H ► d [μπι] FIG. 2. Effect of tidal volume V, and mean residence time t on diifusional deposition in the respiratory tract. 46 C. H. SCHILLER et al Experimental data for mouth breathing Only a small intersubject variability of total deposition was observed. This is in agreement with previous observations that the subjects who volunteered in this study have very similar total deposition (HEYDER, et al 1975). Mean values of total deposition for mouth-breathing are summarised in Table 1.

In the size range considered in this paper the contribution to the size distribution of particles carrying multiple charges is negligible. In a few cases deposition measurements with monodisperse silver aerosols in a diffusion battery showed that the electric mobility-equivalent diameter of the silver particles agrees with their diffusion-equivalent or thermodynamic diameter. Inhalation apparatus The monodisperse silver aerosol continuously passes a neutralizer and then enters an air conditioned box where all parts are kept at body temperature (Fig.

To account for particle losses in the system the spirometer bell was operated manually to simulate the whole pulsatile flow pattern of the breathing experiment. The CNC then measured a particle number concentration xyc0, where c0 is the mean particle number concentration available for inhalation, x is the mean probability that a particle escapes deposition while it is transported from the mouthpiece to the CNC, and y accounts for the concentration change due to the reduction in temperature from body to room temperature when the aerosols leave the air conditioned box.

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