By Hiroshi Nagasawa (auth.), Benjamin S. Leung Ph.D. (eds.)
The idea that hormones impression tumor progress originated in 1889 with the thought of Albert Schinzinger who prompt that breast melanoma is expounded to the ovaries. a number of years later, Sir George Beatson saw that remission of disseminated breast melanoma should be completed in premenopausal sufferers by way of appearing bilateral oophorectomy. due to the contri butions of Hedley Atkins, Charles Huggins and others, additive and ablative hormonal cures were normal for the remedy of complicated breast cancers for numerous a long time. version platforms to check the consequences of hormones on development and regression of breast tumors were to be had for a few years; despite the fact that, the complexities of the hormonal setting have rendered in vivo experiences tricky in guy and experimental animals. lately, the supply of long term cultures of breast melanoma cells has encouraged many investigators to take advantage of those phone strains to solve the mechanisms of hormone motion. end result of the severe variety and complexity of advances concerning the endocrinology of the breast and breast cancers, a multi-authored evaluate was once deemed beneficial. it's been pleasurable to obtain contributions from many famous students. In quantity I of this monograph, the effect of steroid hormones and their antagonists upon general and neoplastic tissues of the mammary gland are offered. In quantity II, the consequences of peptide and different hormones are reviewed.
Read or Download Hormonal Regulation of Mammary Tumors: Volume II: Peptide and Other Hormones PDF
Similar nonfiction_10 books
The elemental fault in high blood pressure is unknown. Calling it a basic fault, certainly, tacitly begs the query: Is there one primary fault, or are there numerous which are interlinked or interdependent? an easy certain or no solution can't be provided. This quantity isn't really designed to survey the updated contemporary advances in learn on high blood pressure, nor meant to supply provisional an swers to the such a lot of unknowns during this subject.
This ebook offers an in depth exam of ways structures situated inside of 5 nations form the early occupation studying of starting academics. It describes, discusses and analyzes finished instructor induction came upon inside France, Japan, New Zealand, Shanghai and Switzerland. We confer with the phenomena we saw as induction ‘systems’ simply because they're am- tious, vast and validated: all starting academics in those quite a few locales are served; there aren't any unfunded mandates; those platforms were in position for 10–25 years.
Built-in experiences at the evaluation and development of soil and water caliber need to deal virtually necessarily with problems with scale, because the spatial aid of measurements, the version calculations and the presentation of effects frequently differ. This booklet comprises the chosen and edited court cases of a workshop dedicated to problems with scale entitled: `Soil and Water caliber at varied Scales', which used to be held in 1996 in Wageningen.
This quantity "Deformation of Ceramic fabrics II" constitutes the lawsuits of a world symposium held on the Pennsyl vania nation college, college Park, PA on July 20, 21, and 22, 1983. It comprises reports of semiconductors and minerals that are heavily with regards to ceramic fabrics.
- Pricing and Cost Recovery in Long Distance Transport
- Multiple Statistical Decision Theory: Recent Developments
- Congenital Displacement of the Hip Joint
- Ultrasound in Medicine: Volume 4
Additional resources for Hormonal Regulation of Mammary Tumors: Volume II: Peptide and Other Hormones
Importance of mammary gland DNA synthesis on carcinogen-induced mammary tumorigenesis in rats. Cancer Res 36: 2223-2226, 1976. 41. Nagasawa H, Yanai R, Taniguchi H. Reduction by pituitary grafts of mammary tumor age. Its variability in a high mammary tumor strain of mice. Effects of mammary DNA synthesis. Eur J Cancer 12: 1017-1019, 1976. 42. Nagasawa H, Yanai R, Taniguchi H, Tokuzen R, Nakahara W. Two-way selection of Swiss albino mice for mammary tumorigenesis: Establishment of new two strains (SHN and SLN).
VanderLaan WP. Influence of nurslng on the release of prolactln and GH in mice with high and low incidence of mammary tumors. Endocrinology 95: 947-54, 1974. 49. Sinha YN, Salocks CB, VanderLaan WP. Prolactin and growth hormone levels in different inbred strains of mice: Patterns in association with estrous cycle, time of day, and perphenazine stimulation. Endocrinology 97: 1112-1122, 1975. 50. Sinha YN, Salocks CB, VanderLaan WP. Circulating levels of prolactin and growth hormone and natural incidence of mammary tumors in mice.
Int J Cancer 6: 488-495, 1970. 27. Nagasawa H, Yanal R. Quantitative participation of placental mammotropic hormones in mammary development during pregnancy in mice. Endocrinol Jpn 18: 507-510, 1971. 20 28. Nagasawa H, Yanai R. Effect of human placental lactogen on growth of carcinogen-lnduced mammary tumors in rats. Int J Cancer 11: 131-137, 1973. 29. Nagasawa H, Yanai R. Some discrepancies between the use of DNA synthesis and wholemount preparations as indices of mammary gland response to pituitary mammotrophin.