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By D Stephen Snyder; Eugenia Wang

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Mediation by corticotropin-releasing factor of adenohypophysial hormone secretion. Ann. Rev. , 48, 475. 12. , Guyre, P. , & Holbrook, N. J. (1984). Physiological functions of glucocorticoids in stress and their relations to pharmacological actions. Endocr. , 5, 25. 13. Dallman, M. , Cascio, C. , Darlington, D. , & Levin, N. (1987). Regulation of ACTH secretion: Variations on a theme of B. Rec. Prog. Horm. , 43, 113. 14. Dallman, M. E, Akana, S. , Bradbury, M. , Strack, A. , Hanson, E. , & Scribner, K.

MEANEY ENDOCRINE, CLINICAL, AND BEHAVIORAL CORRELATES OF SUBGROUPS PHC subjects show progressive increases in plasma cortisol levels over years. Moreover, the most recent plasma cortisol level is also significantly elevated in these subjects. However, there are no obvious differences in the circadian cortisol rhythm in these subjects in comparison to either PMC or NLC subjects (Fig. 1). In addition, there were no group differences in plasma CBG levels in either the AM or PM phase of the cycle. This was further supported by the strong correlation between total and free plasma cortisol levels (measured recently using salivary sampling) across subjects.

R. (1995). Chronic antidepressant treatment improves spatial learning in young, but not aged rats: Correlation with corticosteroid receptor gene expression in the hippocampus. Neuroscience, 66, 571-581. 6. , Baskin, R. , & Pitier, T. A. (1981). Brain-aging correlates: Retardation by hormonal-pharmacological treatments. Science, 214, 581. 7. , & Tyrell, J. B. (1987). The adrenal cortex. In P. Felig, J. D. Baxter, A. E. Broadus, & L. A. ), Endocrinology and metabolism (p. 385), New York: McGraw-Hill.

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