Download Epidemiology and Prevention of Gallstone Disease: by A. Menotti (auth.), L. Capocaccia, G. Ricci, F. Angelico, M. PDF

By A. Menotti (auth.), L. Capocaccia, G. Ricci, F. Angelico, M. Angelico, A. F. Attili (eds.)

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Read or Download Epidemiology and Prevention of Gallstone Disease: Proceedings of an International Workshop on the Epidemiology and Prevention of Gallstone Disease, held in Rome, December 16–17, 1983 PDF

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Additional resources for Epidemiology and Prevention of Gallstone Disease: Proceedings of an International Workshop on the Epidemiology and Prevention of Gallstone Disease, held in Rome, December 16–17, 1983

Example text

Persons not attending are invited a second time. When necessary a third invitation is made by telephone - or by another letter. The morbidity and occupation of non-participants are compared with that of the participants by data from telephone interview and central registers. If any diseases are discovered the participants are informed and referred to their general practitioner. As it is a debatable issue whether or not asymptomatic gallstones necessitate surgery, we are unable to give rational advice for this condition.

M. (1983). Nucleation of cholesterol monohydrate crystals from hepatic and gallbladder bile of patients with cholesterol gallstones. Gut. 24, 836-844 22. Burnstein. M. • IIson. R. • Petrunka. C. N.. Taylor. R. D. and Strasberg, S. M. (1983). Evidence for a potent nucleating factor in the gallbladder bile of patients with cholesterol gallstones. Gastroenterology. 85, 801-807 23. Gill, W. , Ruggiero, K. J. and Fromes, M. C. (1980). Elevation ofthe metastable limits and absence of container surface nucleation for calcium oxalate crystallization in a urotheliallined system as compared to glass containers.

7); it does, however, have a polymeric structure due to hydrophobic and disulphide bonds 40 • '/ MW>2 x 106 SHEAR RATE Figure 7 Structure and properties of mucus. Mucus is a viscoelastic gel having MW> 2 x 106 with viscosity which decreases with increasing shear rate owing to its thyxotropic behaviour 39 . It represents a barrier preventing damage of the gallbladder mucosa-which has phospholipases-and acts as a hydrodynamic lubricant High molecular weight mucus-glycoproteins are secreted in increased concentration in patients with lithogenic bile 41 and in experimental cholesterol-fed prairie dogs 42 • Stones grow gradually by sedimentation around an initial nucleus.

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