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Additional info for Dementia in Clinical Practice: A Neurological Perspective: Pragmatic Studies in the Cognitive Function Clinic
However, it may be the case that the bias involved in such pragmatic studies (small size, single-centre, method- and operator-dependency) means that the findings reflect sample-specific characteristics and hence are difficult to generalise. Clearly there are overlaps between pragmatic diagnostic accuracy studies and the methodology of audit (National Institute for Clinical Excellence 2002). It should be remembered that practical medical knowledge also has a narrative structure (Hunter 1991), since this is the idiom of clinical practice, hence the inclusion in this volume of case material, considerable experience in the writing up of which has been gained (Ghadiri-Sani and Larner 2014).
G. Alzheimer’s disease); change in dietary habit with a predilection for sweet foods may occur in behavioural variant frontotemporal dementia (bvFTD). • Mood: anxiety and depression can impact on memory function, and may be potentially reversible with appropriate medication (see Sect. 2). • Sleep pattern: disturbed sleep may impair memory, for example in depression or specific sleep-related disorders such as obstructive sleep apnoea syndrome or restless legs syndrome (see Sect. 3). • Drug use: both prescription and recreational drugs may impair cognition, for example due to anticholinergic or soporific effects.
1 Family History of Dementia . . . . . . . . . 2 Neurological Examination. . . . . . . . . . . . . 1 “Attended Alone” Sign . . . . . . . . . . . . 2 Head Turning Sign. . . . . . . . . . . . . . 3 Applause Sign . . . . . . . . . . . . . . . 3 Summary and Recommendations. . . . . . . . . . References . . . . . . . . . . . . . . . . . . . . . . 41 45 50 51 58 62 64 66 Abstract This chapter considers important aspects in the clinical history, including family history, in the diagnosis of cognitive disorders, and also examines the diagnostic utility of various non-canonical neurological signs (attended alone, head turning, applause).