Download Behavioral Neurobiology of Schizophrenia and Its Treatment by Neal R. Swerdlow PDF

By Neal R. Swerdlow

This publication describes the cutting-edge of therapy of schizophrenia and displays its improvement in 22 chapters written by means of best gurus within the box

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Additional info for Behavioral Neurobiology of Schizophrenia and Its Treatment (Current Topics in Behavioral Neurosciences, Volume 4)

Sample text

The CATIE data also highlighted the high prevalence of metabolic disorders in chronic schizophrenia patients, and the moderating role of gender and race or ethnicity in antipsychotic-associated metabolic adverse effects. In the post-CATIE era, safety concerns remain the primary driver of antipsychotic prescribing habits. Absent compelling efficacy data that differentiates between antipsychotics for nonrefractory schizophrenia, the CATIE results reinforce the need for additional metabolically neutral antipsychotic treatment options, and the importance of ongoing physical health monitoring for schizophrenia patients.

2003), but the largest published study at that time was from a Canadian sample of 240 subjects (Cohn et al. 2004). Of 1,460 subjects with baseline data, 689 CATIE subjects had fasting laboratory measures at study baseline to examine metabolic syndrome criteria, and these subjects were matched 1:1 on the basis of age, gender race, and ethnicity with subjects randomly drawn from the Third National Health and Nutrition Examination Survey (NHANES III) to perform comparative analyses. 9% (McEvoy et al.

1 Metabolic Outcomes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2 Framingham Cardiovascular Risk . . . . . . . . . . . . . . . . . . . . . . . . . . 3 Outcomes with Novel Biomarkers . . . . . . . . . . . . . . . . . . . . . . . . . . 33 5 The Post CATIE Era . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 Clinical Conclusions .

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