By J. Rick Turner, L.R. Cardon, John K. Hewitt
Leading researchers learn how habit genetics presents an important insights into genetic and environmental affects within the improvement of biobehavioral issues. those impacts are illustrated through the use of the examples of heart problems, weight problems and consuming problems, alcohol use and abuse, and smoking habit. participants speak about the relevance of molecular genetic techniques and dual and kinfolk designs to the advanced box of habit drugs research.
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Extra resources for Behavior Genetic Approaches in Behavioral Medicine
Porjesz, B. (1990). Neuroelectric processes in individuals at risk for alcoholism. Alcohol and Alcoholism, 25, 251-256. , & Kissin, B. (1984). Event-related brain potential in boys at risk for alcoholism. Science, 225, 1493-1496. , Noble, E. , Sheridan, P. , Briggs, A. , & Cohen, J. B. (1990). Allelic association of human dopamine D2 receptor gene and alcoholism. Journal of the American Medical Association, 263, 2055-2060. , & Cloninger, C. R. (1981). Maternal inheritance of alcohol abuse: Cross-fostering analysis of adopted women.
Identical twins, or monozygotic (MZ) twins, share 100% of their genetic material identical by descent, while nonidentical twins, or dizygotic (DZ) twins, share, on average, only 50% of their genetic material. , the equal environmental similarity assumption). Because the logic of the classic twin study depends so critically on the validity of this assumption, the equal environmental similarity assumption has received significant empirical attention in the behavior genetics literature (Loehlin & Nichols, 1976; Plomin, DeFries, & McCleam, 1990; Kendler, Neale, Keisler, Heath, & Evans, 1993).
05). ns et al. (1991) and McGue et al. (1992) samples overlap. 3a INHERITANCE OF ALCOHOLISM 25 there are several notable features of the summary. First, for males, MZ twin concordance is consistently larger than DZ twin concordance, implicating the importance of genetic factors. Second, the MZ twin concordance for alcoholism is always substantially less than 1, implicating the importance of nonshared environmental factors. Finally, as was the case with adoption studies, findings from studies of female twins might be taken to suggest that genetic influences on alcoholism risk may be weaker among women than among men (McGue, 1993).