By Soumya Banerjee, Drew Levin, Melanie Moses, Frederick Koster, Stephanie Forrest (auth.), Pietro Liò, Giuseppe Nicosia, Thomas Stibor (eds.)
This publication constitutes the refereed lawsuits of the tenth foreign convention on man made Immune structures, ICARIS 2011, held in Cambridge, united kingdom, in July 2011. The 37 revised complete papers have been rigorously reviewed and chosen from various submissions. The papers are prepared in topical sections on immunoinformatics and computational immunology; idea of immunological computation; and utilized immunological computation.
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Extra info for Artificial Immune Systems: 10th International Conference, ICARIS 2011, Cambridge, UK, July 18-21, 2011. Proceedings
For similar reasons, the above relations are transitive. forall xyz (implies (and (communication x y) (communication y z)) (communication x z)) Topology in the lymphatic system. We distinguish two main types of component in the lymphatic system: i) lymphatic vessels and ii) lymphatic nodes. Lymphatic vessels are conduits along which lymph ﬂows. They form a network that is marked out by the nodes. Lymphatic nodes are encapsulated lymphoid tissues with sinuses contiguous with the lumen of aﬀerent and eﬀerent lymphatic vessels.
A core ontology of the immune system, in contrast, will focus on the particular and speciﬁc aspects, entities, and phenomena that characterise the domain as such. In the present paper, we are primarily concerned with only a portion of the core ontology of the immune system: the minimum portion of a core ontology of the immune system that is required to articulate accounts of that system’s main topological aspects. In its more diminutive expression, this portion ought to be reduced to the topology of lymphoid tissues and lymphatic vessels at the scale at which translocation of immune agents occurs within the body.
The Ag is the target of the immune response. Th and B lymphocytes are responsible for the discrimination of the self-nonself, while PLBs produce antibodies able to label the Ags to be taken by the APCs, which represent the wide class of macrophages. Their function is to present the phagocytised antigens to T helper cells for activation. The ICs are Ab–Ag ties ready to be phagocytised by the macrophages. ) whose size is plotted in order to quantify group presence, aﬃnity driven interactions, mutations, clonal selection and all of the processes detailed above.