Download Advances in Virus Research, Vol. 62 by Karl Maramorosch, Frederick A. Murphy, Aaron J. Shatkin PDF

By Karl Maramorosch, Frederick A. Murphy, Aaron J. Shatkin

The Advances in Virus study sequence covers a various diversity of in-depth studies delivering a precious review of the present box of virology. This eclectic quantity includes six stories overlaying issues on the subject of plant viruses, evolution of viruses with hosts and telephone reputation by way of viruses. Six accomplished studies on: * Varicella Virus - Mononuclear telephone interplay * Evolution of mobilephone attractiveness by means of Viruses: A resource of organic Novelty with clinical Implications * Infectious Pancreatic Necrosis Virus: Biology, Pathogenesis and Diagnostic tools * constructions of Picrona-like plant viruses: Implications and functions * Cucumoviruses * Co-Evolution of Viruses with Hosts and Vectors and attainable Paleontology

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2001; Eigen and Biebricher, 1988). , 1976; Drake and Holland, 1999), values that imply the continuous generation of dynamic mutant distributions in a replicating RNA virus population. These high mutation rates in RNA genomes would be incompatible with maintenance of the genetic information contained in large viral or cellular DNA genomes (Eigen and Biebricher, 1988). This evolutionary adaptation of mutation rates is mirrored in the biochemical activities of the relevant DNA and RNA polymerases.

2003). EVOLUTION OF CELL RECOGNITION BY VIRUSES 45 C. Virus–Receptor Interactions Revealed by Structural Studies The specific interactions between a viral protein or glycoprotein and receptor molecules are amenable to structural studies, and such studies are providing essential new information for the understanding of virus–receptor interactions. Enveloped viruses, such as HIV, attach to host cells by means of spike-like membrane glycoproteins, whereas most nonenveloped viruses, such as picornaviruses, attach by means of specialized domains integral to their capsids.

Other examples of the use of several receptor types by a virus include adenoviruses, coronaviruses, hepatitis C virus, influenza virus, measles virus, and rabies virus (references and additional examples in Table III and Section IV). B. , 1976). , 2001). , 1997). These viruses belong to immeasurably distant families and are associated with unrelated diseases. Adenoviruses 2 and 5 are agents of respiratory disease in children, whereas coxsackieviruses B1 to B6 may be associated with febrile illness, meningitis, and some types of cardiopathies.

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